| Anavex Advances Drug Candidate For Treatment Of Alzheimer's Disease
Anavex Life Sciences Corp. ("ANAVEX") (OTCBB: AVXL) is pleased to announce promising developments with ANAVEX 1-41, the company's lead drug candidate for Alzheimer's disease. In recent pre-clinical animal studies, ANAVEX 1-41 prevented oxidative stress, which damages and destroys cells and is believed to be a primary cause of Alzheimer's disease. ANAVEX 1-41 also prevented the expression of caspase-3, an enzyme that plays a key role in programmed cell death and in the loss of cells in the hippocampus, the part of the brain that regulates learning, emotion and memory.
The results are further highlighted in that this activity involves both muscarinic and sigma-1 receptor systems indicating a novel mechanism of action. Published results were presented at the Neuroscience 2007 conference in San Diego, California, and are available at http://www.anavex.com/publications.html.
Processed Meat Unsafe For Human Consumption; Cancer Experts Warn of ...
World cancer experts have finally declared what NewsTarget readers learned nearly four years ago: That processed meats cause cancer, and anyone seeking to avoid cancer should avoid eating all processed meats for life.
Hundreds of cancer researchers took part in a five-year project spanning more than 7,000 clinical studies and designed to document the links between diet and cancer. Their conclusion, published in the World Cancer Research Fund's report, Food, Nutrition, Physical Activity and the Prevention of Cancer: a Global Perspective (2007), has rocked the health world with a declaration that all people should immediately stop buying and eating processed meat products and that all processed meat should be avoided for life!
Processed meats, the report explains, are simply too dangerous for human consumption.
Methyl bromide still finds its way into U.S. fields
Methyl bromide, a common pesticide and fumigant used to kill everything from worms to termites, is at the top of the agenda of the Multilateral Fund for the Implementation of the Montreal Protocol, that reconvenes next week in Quebec. It is targeted because it harms the ozone layer, exposing the Earth to ultraviolet sunlight. While the United States is technically in compliance with the protocol, the federal government frequently uses a policy that allows it to apply for critical-use exemptions. There is no limit to the number a country can request, and the United States has been able to continue with as much as 30 to 40 percent of its original methyl bromide use. Sixty percent of all exemptions are sought by the United States, and this number could increase as other countries curtail their use.
Obesity conceals cancer
The most common blood test for prostate cancer often fails to catch early signs of the disease in obese men because they have more blood than other patients, according to a new study.
The research suggests that levels of prostate-specific antigen, or PSA, might appear lower in obese men, thus delaying diagnosis and treatment of the cancer.
"When we get to the point when PSA is elevated in obese men, we find cancer that's more advanced," said Dr. Alan W. Partin, chairman of urology at Johns Hopkins Hospital and co-author of the study. "When cancer is detected in a later stage, it has much worse outcomes, and it's harder to cure."
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